Leuko reduction is the process of removing white blood cells (leukocytes) from donated blood. The removal of leukocytes is important because it reduces the risk of transfusion-associated complications such as fevers, infections, and immune reactions. These complications can occur because leukocytes in the transfused blood can trigger an immune response in the recipient's body.
Leuko reduction can be achieved using different methods such as filtration or centrifugation. Filtration is the most common method and involves passing donated blood through a filter that traps leukocytes. Centrifugation involves spinning the blood in a specialized machine that separates the leukocytes from the rest of the blood components.
Leuko reduction is recommended for certain types of blood transfusions such as those given to people who are immunocompromised, critically ill patients, and pregnant women. However, it may not be necessary for all transfusions and should be determined on an individual basis by the healthcare provider.
Overall, leuko reduction is an important step in ensuring the safety and effectiveness of blood transfusions, as it reduces the risk of complications and improves patient outcomes.
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